Imaging
The core application for scanning ion conductance microscopy (SICM) is topographic imaging. In particular, SICM specialises in the imaging of soft surfaces in liquid, such as living cells, polymers, lipid rafts etc and as such has particular relevance in the area of life-science ¹’²’.
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¹ Novak, P., Li, C., et al. (2009). "Nanoscale live-cell imaging using hopping probe ion conductance microscopy." Nature Methods, doi:10.1038/nmeth.1306
² Shevchuk, A. I., G. I. Frolenkov, et al. (2006). "Imaging Proteins in Membranes of Living Cells by High-Resolution Scanning Ion Conductance Microscopy." Angew Chem Int Ed 45(14): 221216
